Donna Mitchell / Mrs. Warren
Terence Rigby / Dr. Edward Staunton
Jennie Eisenhower / Girl at the Station

Brian Tarantina / Crazy Hair Driver
Justin Bartha / Jasper Bernard
David Greenspan / Francis, the Director
Dagmara Dominczyk / Pamela
Caroline Schlobohm / Shannon
Eva Mendes / Faith Faison
Sterling K. Brown / Rand
Teresa Yenque / María, the Babysitter
Kiran Merchant / Newspaper Vendor
Tom Riis Farrell / Waiter
Cal Freundlich / Cosmos
Ellen Barkin / Norah
Jayne Houdyshell / Sex Addicts Leader
Todd M. Hofacker / Misplaced Sex Addict
Peter S. Bencebi / Cynical New Yorker
Kate Jennings Grant / Woman Who Can't Get Enough
Frederick B. Owens / John, Preferably Coarse
Jim Gaffigan / Gordon, Bitter Sex Addict
James Le Gros / Dante
Steve Glenn / Rocker at the Bar
Glenn Fitzgerald / Goren
Paul Hecht / Amis
Steven Wargo / Dinner Guest
Sherry Ham-Bernard / Lincoln Center Fan
Gretchen Cleevely / Assistant Stage Manager
John Ellison Conlee / Usher
Sean Dugan / Stage Manager
Hollis Granville / Stage Actor
Jimmy King / Audience Member #1
Chris Champeau / Audience Member #2
Francine Beers / Old Lady
Liv Freundlich / Older Maggie
Noelle Beck / Flight Attendant
Jacqueline Lovell / Bar Girl (unconfirmed)
Chenoa Andon / Theatre Patron
Anya Avaeva / Spectator
Bob Balaban / Tobey's Therapist
Cher Cosenza / Cocktail waitress
Emrie Foster / Cousin
Bart Freundlich / Man on the street
Claudia Lopez / Club Goer
Cristina Marie / Theatre Patron
Josh Ruben / Elaine's Brother
Mario Simone / Skateboarder
Jen Strickland / Rachel
Boomer Tibbs / Sex Addict Group Member

Chin Han / Lau
Nestor Carbonell / Mayor
Eric Roberts / Maroni
Ritchie Coster / Chechen
Anthony Michael Hall / Engel
Unknown / Unknown