Carol Kane / Cousin Tilly /  Mrs. Hatch
Bronson Pinchot / Mr. Carter
Dan Lauria / Bert
Craig Sheffer / Ernie Bishop /  Ed /  Bridgekeeper
Armelia McQueen / Mrs. Thompson
Ryan Slater / Young George Bailey /  Pete Bailey
Tina Majorino / Janie Bailey
Myles Jeffrey / Tommy Bailey
Mae Whitman / Zuzu Bailey

Martin Landau / Papa Gruber
Bruce Greenwood / Myles Billingsley
Anne Bancroft / Mama Gruber
Kenneth Welsh / Harry Truman
Jamie Arguy / Asylum Refugee
Aaron Ashmore / Myles Billingsley Jr.
Yank Azman / Papa Stern
Hume Baugh / Karl
Brenda Bazinet / Lili
Jessica Beitchman / Eva's Cousin
Sharon Bernbaum / Beata Stern
Wayne Best / Phil
David Lawrence Brown / Reporter #1
Christine Brubaker / Peach
Leslie Carlson / Old Man
Dmitry Chepovetsky / Refugee Man
Jeff Clarke / Ralph Faust
Bruce Clayton / Willard Miller
Vince Corazza / Cody
Alyson Court / Bernice
Philip Craig / Arlen Lloyd
Eve Crawford / Helen
Gordon Currie / Jimmy
Martin Doyle / Sen. Fricker
David Dunbar / Hitler
Conrad Dunn / Josef
Craig Eldridge / Sgt. Driscoll
Donna Goodhand / Enid Billingsley
Janet-Laine Green / Eleanor Sayles
Zoe Heath / Sophie
Brittany Kay / Rose (Sophie's Daughter)
Ron Kennell / Reporter #2
Luke Kirby / David Weinzweig
Ken Kramer / Army Camp Rabbi
Sid Kroach / Rose
Mark Antony Krupa / Willy
Nancy McAlear / Millie
Trent McMullen / Tom
Mike McPhaden / Military Man
Marnie McPhail / Tex
Magdalena Alexander / Pregnant Woman
Jane Moffat / Truman's Secretary
Duane Murray / Military Police Officer
Brooke Nevin / Terri Sayles
Jack Newman / David's Uncle
Dave Nichols / Capt. Lester
Joanna Schellenberg / Fanny
John Watson / German SS Man
Jonathan Watton / Henry
John White / Ben Billingsley
Jonathan Whittaker / Army Colonel
Kathryn Winslow / Marie Minucci
Ned Vukovic / Nathan
Timm Zemanek / Professor
Nic Bambrough / Extra (Refugee)
Scotty Cook / Young Child
Ilke Hincer / Refugee /  Concentration Camp Survivor
Alexander O'Neill / Young Refugee 2
Michael Sercerchi / Military Police Officer

Martin Landau / Frank Malone
Eric Scott Gould / Chuck
Vanessa Marano / Hanna Malone
Laura Marano / Kate Malone
Julie Pop / Leslie Walters
Kimberly Cass / ND Agent
Michael Papajohn / Unshaven Man /  Tom
L.B. Tracey / Young Jack

Scott Beehner / Co-Worker #4
Todd Fink / Fancy Waiter
Ross Brockley / Grumpy Carriage Driver
Alex Curbeam / Damien Montgonmery
Michael Leach Jr. / Sled Kid #2
Nick Hernandez / Sled Kid #3
Leo Fitzpatrick / Pharmacist
Judith Kathryn Hart / Jacky
Jules Blight / Lisa
Mark Booker / Harold
Mark Kresl / Rufus
Zoey Newman / Michelle
James Devney / Buck
Melissa Jarecke / Party Woiman
Sean O'Connell / Young Mike
Randi-Shane Knox / Young Alex
Chuck Martens / Extra
Danielle Smith / Extra
Brett Comstock / Girl in Cafe (uncredited)
Andrea Marzullo / Ghost (uncredited)
Candice Rose / Young Mary (uncredited)