Mindy Sterling / Clarnella
Rachel Winfree / Rose
Rance Howard / Elderly Timekeeper
Jeremy Howard / Drew Lou Who
T.J. Thyne / Stu Lou Who
Lacey Kohl / Christina Whoterberry
Nadja Pionilla / Junie
Jim Meskimen / Officer Wholihan
Michael Dahlen / Customer
David Costabile / Biker Who
Mary Stein / Miss Rue Who
James Ritz / Crazy Mose
Deep Roy / Post Office Clerk
Jessica Sara / Sophie
Mason Lucero / Who Boy
Ben Bookbinder / 8-Year-Old Augustus Maywho
Michaela Gallo / Who Schoolgirl
Landry Allbright / 8-Year-Old Martha May Whovier
Reid Kirchenbauer / 8-Year-Old Whobris /  Kid
Rebecca Chace / Shopper
Suzanne Krull / Shopper
Steve Kehela / Shopper
Lillias White / Shopper
Rain Pryor / Shopper
John Alexander / Shopper
Kevin Isola / Tree Trimmer
Gavin Grazer / Yodeler
Walter Franks / Clerk
Verne Troyer / Band Member
Clayton Martinez / Cook
Q'orianka Kilcher / Little Choir Member
Caroline Williams / Tiny Who Woman
John Short / Tiny Who Man
Grainger Esch / Near Miss Who
Eva Burkley / Pudding Chef
Rick Baker / Puppeteer
Bill Sturgeon / Puppeteer
Mark Setrakian / Puppeteer
Jurgen Heimann / Puppeteer
Tim Blaney / Puppeteer
Bryce Dallas Howard / Surprised Who (as Bryce Howard)
Charles Croughwell / Balloon Who
Frank Welker / Max the Dog (voice)
Jack Angel / Santa Claus
Rachel Bailit / Sexy Whoville Nurse
Dean Chambers / Who
Paul Eiding / Echo
Mindy Ferguson / Sexy Blonde Who
Heather Lea Gerdes / Whoville Choir
Linda Harmon / Whoville Choir
Richard Steven Horvitz / Grinch's Answering Machine (voice)
Ron Howard / Whoville Townsperson
Seth Adam Jones / Hugh Who
Tommy Karlsen / Additional Voices (voice)
Allie McCall / Noelie
Christopher Metas / Who
Ann Mills / Shopper
Sloane Momsen / Little Girl Dreaming of Sugarplums
Bonnie Morgan / Pudding Head Who
Danuta Parsons / Who
Frankie Ray / Who
Ellyse Santoro / Who
Robin Kaye Shaw / Toy Lady Who

Eric Poppick / The Banker
Ernie Sabella / Maury, the Cat Care Society Owner
William Hickey / Rudolph Smuntz
Christopher Walken / Caeser, the Exterminator
Cliff Emmich / Mayor McKrinle
Melanie MacQueen / Mayor's Wife
Brianna Shebby / Becky
Danielle Shebby / Betty
Leslie Upson / Leslie Reinhart
Mario Cantone / Zeppco Suit #1
Peter Anthony Rocca / Zeppco Suit #2
Steve Bean / Lester Dinkus
Suzanne Krull / Waitress #1
William Frankfather / Mr. Texas
Patrick Thomas / Construction Worker #1
Peter Gregory / Doctor
E.J. Callahan / Historical Clerk
Susan Blommaert / Ms. Park Avenue
Valorie Armstrong / Franklin's Wife
Michael X. Sommers / Paramedic
Michael K. Ross / Cop
José Rey / Cuban Postal Worker
Carmen Filpi / Pallbearer #4
Harper Roisman / Factory Worker #1
David Fresco / Factory Worker #2
Michael Laren / Drowning Waiter
Scott Alan Smith / City Paramedic
Sarah Dampf / Crying Child
Orville Stoeber / Expert #1
David Weisenberg / Expert #2
Fred Pierce / Large Nosed Man
Clement Blake / Homeless Man
Saverio Carubia / Photographer
Pep Torres / Bus Boy
Jack Angeles / Kennel Employee
Greg Bronson / Neighbor
Whit Hertford / Vinny

William Fichtner / Burke
Rita Bland / Dancing Register Woman
Tony Denman / Track Suit Guy
Scott Hass / Raver Dude
Natasha Melnick / Anorexic Girl
Manu Intiraymi / Skate Punk Guy
Josh Paddock / Spider Marine
Taye Diggs / Marcus
Breckin Meyer / Tiny
James Duval / Singh
Courtland Mead / Boy
Katharine Towne / Becky
Marisa Johnston / Rebecca
Ken Kupstis / Sports Car Man
Nikki Fritz / Noelle
Tane McClure / Holly
Jimmy Shubert / Victor Jr.
J.E. Freeman / Victor Sr.
Jay Paulson / Loop
Jane Krakowski / Irene
Melissa McCarthy / Sandra
Shann Christen / Jimmy
Willie Amakye / Waiter
Princess Leah Lucky Buttons / Alley Cat
Emmy Collins / Longhair in Supermarket
Sean Everett / Shooting Bartender
Sebastian Feldman / Insomniac in Diner
Walter Ludwig / Strip Club Patron
Bob Pepper / BlackJack & Slot Player
Dana Schick / Girl in Line
Mark Sharp / Police Officer
Bill Swann / Elevator Man
J. Karen Thomas / Nurse
D. Danny Warhol / Mary X-Mas Supa Fest Dancer
Algerita Wynn / Shopper
Monique Yates Jr. / Yellow Jacket